HuMiX – The artificial gut

Effects of the Artificial Sweetener Neotame on the Gut Microbiome and Fecal Metabolites in Mice.

Although artificial sweeteners are widely used in food industry, their effects on human health remain a controversy. It is known that the gut microbiota plays a key role in human metabolism and recent studies indicated that some artificial sweeteners such as saccharin could perturb gut microbiome and further affect host health, such as inducing glucose intolerance. Neotame is a relatively new l...

Impact of the Gut Microbiota on Vaccine Responses

Non-responsiveness or poor responsiveness to vaccines are challenging issues in vaccine development, and efforts have been made to find out the potential reasons for these conditions. Intestinal microbiome plays a key role in regulating and development of immune system and the composition and diversity of microbiota in different individuals on the one hand, and the imbalance of intestinal micro...

Case of Strangulated Inguinal Hernia, with Gangrene of the Gut: Recovery, with Artificial Anus

of great prostration and suftering. He was scarcely able to speak, but bis friends stated that the rupture came down 12 days before, and since then he had not been able to return it into the cavity of the abdomen. During all that time there had been no passage from his boweta, and up to within two days of his admission he had vomited severely. I was unable to ascertain whether the vomiting was ...

The effect of artificial rearing on gut microbiota in a mouse pup-in-a-cup model.

In this paper, the mouse pup-in-a-cup model was improved for younger mouse pups, and the effect of artificial rearing on gut microbiota development was evaluated. Intragastric cannulas were placed through the esophagus into 3-day-old C57BL/6J mice (n=48), and the mice were artificially reared (AR) with mouse milk substitute (MMS). Littermate pups (n=20) were maternally reared (MR) as controls. ...

Gut Microbiota and Neuropsychiatric Disorders